I am Alessandro, physicist trained in biophysics and biology. My track record will tell you that my research is quite eclectic as I have published work across various disciplines, spanning information theory, sensor technologies, molecular biology and cell biology. I love to tinker with technology, develop new algorithms and software and I am best known for these aspects of my work. However, the molecular mechanisms of disease (neurodegeneration, malaria and cancer) have been always at the focus of my biophysical developments. The passion for science and technology can be even more rewarding when addressing problems which solution can have high societal impact. Cancer biology is my passion since 2010, a field where I believe I can make an impact. Since a few years, I lead a team of scientists dedicated to transdisciplinary research aimed to enable a live single-cell systems biology of cellular decisions and to apply these tools for a better understanding of carcinogenesis.
Short biosketche for conferences
Dr Alessandro Esposito obtained a PhD in Biophysics in 2006 working at the University of Utrecht and the European Neuroscience Institute in Goettingen for which he was awarded the ‘Sergio Ciani’ award by the Italian Society of Pure and Applied Biophysics. At the University of Cambridge, he then applied quantitative imaging techniques contributing to define better models of red blood cells homeostasis infected by P. falciparum (malaria). In 2009, Alessandro was awarded a Life Science Interface fellowship by the EPSRC to establish foster the development of biochemical multiplexing imaging. Since then, he has refocused his research on cancer biology leading a transdisciplinary research programme at the MRC Cancer Unit in Cambridge. While breaking new ground in live single-cell biochemistry, Alessandro is depicting a fresh perspective on cellular decisions in response to stress by investigating the roles of genetic and non-genetic heterogeneity, and cell-to-cell communication, in cell fate choices during carcinogenesis.